Introducing the alphaRS Pro

a powerful electrophysiology system that records up to 1024 neural signals and delivers precise stimulation with real-time closed-loop control. With an open API for seamless integration, it's perfect for animal and clinical research, supporting multiple Headstages and headboxes. Experience the future of electrophysiology with alphaRS Pro.

alphaRS Pro at a Glance

  • Up to 1024 High resolution Neural Recordings Channels
  • Online & Flexible Signal Processing
  • Fully Customizable Experimental Control
  • Real-Time Closed-Loop Processing
  • Integrated Advanced Electrical Stimulation
  • Online Analysis Display
  • Simple and Flexable User Interface
  • Impedance Measurements
  • System Cascading
  • Digitized, Small and lightweight headstages

 

"We developed novel electrodes and needed a recording and stimulation system that could support more than 32 channels, record EMG, and deliver arbitrary stimulation up to 2.5mA per channel. Most importantly, we required an SDK to integrate our algorithms for advancing our EMG+stim technology. The AlphaRS Pro delivered all these features, making it the perfect solution for our research and development needs."
— Raz Karl, CTO, BlinkAid

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1024 CH & Advanced Signal Processing

supports up to 1024 channels with real-time, flexible filtering for microelectrode recordings, including Spikes, LFP, EEG, ECoG, and EMG, ensuring high-quality data across diverse applications.

Online Analysis Display

Built-in Spike Raster and Montage tools, providing real-time analysis and visualization of neural activity during experiments.

Impedance Measurments

Built-in impedance check for continuous monitoring, ensuring optimal electrode performance and data accuracy throughout the experiment.

Online data streaming and full system control

User-friendly API supporting MATLAB, C++, and C#, allowing full interface customization. Designed for closed-loop experiments and BCI/BMI applications, offering maximum flexibility and control.

Integrated Electrical Stimulation

Supports up to 256 stimulation channels with customizable pulse options, controlled via API or user interface. Choose between serial or parallel stimulation modes for flexible experiment design.

Real-Time Closed-Loop Functionality using C++

Achieve real-time, fast closed-loop processing with the alphaRS system's C++ API, enabling rapid data analysis, display, and trigger outputs within 1.5 milliseconds.

 

Up to 1024 channels. Compact & portable data acquisition system with expandable channels

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Online data streaming and full system control. User-friendly API for two-way communication using MATLAB, Phyton, C#, or C++ for streaming all data and control system functionality.

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Integrated Electrical Stimulation: With integrated electrical stimulation, up to 256 contacts can record and/or stimulate. Mode of the contact (recording or stimulation) can be controlled by the system’s API or user interface. 
- Use only one software and one hardware to control your neuromodulation experiments!

Impedance check: Built-in impedance check for all contacts, allowing the user by one click to check the electrode’s impedance during any stage of the experiment.

Closed Loop/BMI/BCI support. Low latency C++ API specially designed for advanced uses (BMI/BCI/Closed-loop experiments). Our C++ API runs under Windows OS and it can reach 1.5mS closed loop.

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Digitized Headstages. Ultra-small and lightweight headstage suitable for all types of setups and subjects.

Analog/Digital inputs and outputs: Embedded digital and analog input that allows connection to external sensors; SDK enables access and control of sensors and actuators 

Online Statistics: Spike raster, and evoked potential.

Online & Flexible Filtering: Real-time streaming of 4 signal types for each contact –> RAW, Spikes, LFP's & Segmented spikes.

User friendly GUI. Modern and User-friendly graphic user interface, with a customizable workspace and the ability to control 3rd party systems. Displayed different groups of channels with different filters. GUI uses GPU to display up to 2K channels.

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Complete Control & Data Access using Alpha Omega SDK

  • Data streaming. All data collected by the AlphaRS can be accessed online in MATLAB, Python, C# & C++.
  • Full system control. From within MATLAB, commands can be sent to adjust almost all system parameters or trigger unique stimulation paradigms.
  • Rich API packages: 4 available API packages with the most common programming languages: MATLAB, Python, #C, C++20231107130233.880.png
  • Closed-loop functionality. Data can be analyzed online, and results can directly trigger digital outputs or stimulation20231107130359.913.png
  • Easy programming. Specially designed MATLAB/Python toolbox and instructions make accessing data in MATLAB/Python simple and easy
  • Endless possibilities. Online access to data means each user can code paradigms specifically for their unique needs

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Features

Specifications and Options

Data Acquisition System

1024 channels real-time Data Acquisition
Stimulation Up to 256 electrical sources, any channel can be automatically switched from recording mode to stimulating
Impedance   One-Click online impedance check for
all contacts 

SW Filtering

 4 Selectable software digital filtering per channel (0.02Hz to 10KHz)

API packages

Online data streaming and full system control by:
Python,MATLAB, C++,C#

General purpose digital outputs

16 digital outputs, Synchronization TTL output

General purpose analog outputs

8 analog outputs ± 5.0 V, 16-bit analog outputs

General purpose digital Inputs

8 digital input channels (TTLs)
16-bit digital input port

General purpose analog Input

8 analog inputs
16 bit-resolution and dynamic range of ±5V

PC interface

Thunderbolt port (20Gbps or 40Gbps)

Power supply

4-pin DC power connector (100-240 VAC, 50-60 Hz)

HeadStage connectivity

8 HeadStages with USB-C connectors, fully isolated ports

LED Indicators

Indicating general system’s state

System size

36 x 26 x 9 cm

PC Specs

 

 CPU

i9 – Base-Clock at least 2.6Ghz

 RAM

32GB 

 Disk

 512GB NVMe SSD
GPU Nvidia GPU, at-least GTX1650 
Interface ports

1x Thunderbolt port

 OS

 Window 10 pro

 

The headstage is an integral part of your experimental setup, the size, and spec can have a huge impact on the subject’s behavior, therefore affecting the end results.

Alpha Omega is offering the smallest headstages in the market starting from 0.25 grams. We offer a variety of Headstages for a wide range of subjects and setups. Our headstages can record all types of electrophysiology signals and have integrated stimulation sources and sensors.

Compatible with a large number of available electrodes in the market

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AO Headstages at a Glance

    • Supporting all types of Brain and electrophysiology signals: MER / EEG / EMG / ECOG / AKG
    • Various headstage configurations: 16CH / 32CH / 64CH / 128CH
    • Integrated stimulation
    • Low noise 2.4μV RMS
    • Integrated 3-axis accelerometer sensor
    • Built-in impedance check
    • Flexible cable length
    • Plug and play with most electrodes in the market

HeadStage compatible electrodes

Our headstages are compatible with numerous commercially-available electrodes, for information contact us.

The headstage connector can be customized per order

 

Headstage Specification

Parameter

Value

Headstage Configurations
  • 16CH recording
  • 16CH recording and stimulation
  • 16CH recording with accelerometer
  • 16CH EMG recording
  • 16CH EMG recording with accelerometer
  • 32CH recording
  • 32CH recording and stimulation
  • 32CH recording with accelerometer
  • 64CH recording
  • 64CH recording with accelerometer
  • 128CH recording with accelerometer

Input Connector
  • 18-pin Omnetics (16 channels HS)
  • 36-pin Omnetics (32 channels HS)
  • 36-pin Omnetics (16 EMG channels HS)
  • 2x 36-pin Omnetics (64 channels HS)
  • 2x 34-pin Molex (32 or 64 channels HS)
  • 4x 34-pin Molex (128 channels HS)

Hardware Filter

Software-controlled high and low pass

filters, to set the bandwidth of the

signals received from the Headstage 0.1 Hz-15KHz is the controlled range, the

default is 1hz to 10Khz

Total Gain

192

Dynamic Input range

± 5mV

Input Type

Unipolar input (1 analog reference and 1 ground)

Note: EMG HS has bipolar input; each channel has it is own reference contact.

A/D Resolution

16 bits

Input Bit Resolution

152 nV

Sampling Rate at HS*

30,000 Samples per second

Input Referred Noise (RMS)

< 2.4μV @ ground

Stimulation Sources

Each channel has it is own stimulation source

Stimulation Pulse Width

10 μs - 1 ms

Stimulation amplitude

1uA - 2.55mA

Voltage compliance

± 7V 

Stimulation frequency

1 Hz to 300 Hz

Impedance Check

Measured, calculated, and reported – Possible to check with different frequencies and different amplitudes

Headstage interface cable

The default is 2 meter; it can be customizable up to 6 meters