The MicroGuide Pro™ has an 8 channel recording capability (special configurations of more than 8 channels are available upon customer request). These can be split between spikes, local field potentials (LFP), electromyography (EMG), or any other auxiliary channels (such as EEG, EOG, ECOG) - a flexibility that is unsurpassed. The MicroGuide Pro™ can easily connect to other systems and is equipped with both analog and digital input / output connectivity. The unit can connect to such devices as a goniometer or IOI modules through TCP/IP. On-line capabilities include spike sorting with template matching and a plethora of other statistical tools.
With integrated micro and macro stimulation, the neurosurgeon can instantly switch from recording to stimulation, to achieve maximum precision in DBS placement. The system is designed for efficiency and ease of use, as the entire operation can be controlled from within the sterile field using the hand-held control pad. For the surgeon’s convenience, information for all system components as well as neural activity is displayed on one screen. In addition, the entire trajectory can be annotated to reflect significant events and brain structures as the electrode passes through them. These features and many more, set the MicroGuide Pro™ apart from any other MER system currently available.
MicroGuide Pro™ Optional Add-On
β Oscillation Algorithm Guiding System and Goniometer Evoked Potentials Module
Alpha Omega continues to lead innovation by offering a new optional module for the MicroGuide Pro™, which further simplifies the surgery procedure and ensures that the correct target has been found by the surgeon.
Based on an algorithm developed by renowned researcher Dr. Hagai Bergman, the Alpha Omega Guiding System module offers users an additional back-up to ensure the correct target has been effectively located. According to the latest research by Dr. Bergman, the spatial extent of the dorsolateral oscillatory region, which overlaps the motor territories of the STN, predicts the outcome of STN DBS. In addition, specific b-oscillation frequencies in the dorsolateral oscillatory region predict the response of Parkinson’s disease motor symptoms to DBS and medication. The research therefore suggests that optimization of DBS outcome in patients with Parkinson’s disease could be achieved by intraoperative analysis of STN b-oscillations by microelectrode or macroelectrode recording (Chen et al., 2006). Optimal DBS outcome would be achieved by selecting the trajectory with maximal dorsolateral oscillatory region length and by placement of the DBS contact in proximity of the STN dorsolateral oscillatory region centre.
Below: Visual Targeting - β Oscillation Algorithm Guiding System and Goniometer Evoked Potentials Module
This module will enable surgeons to now fully visualize the reaction to patient passive hand movement and stimulation during the procedure. Previously this process depended solely on audio signals to measure patient responsiveness.